Archive for the ‘Healthcare’ Category

The Importance of DHA – Part 2 (Omega-3s vs Omega-6s and The Plight of Humans, Whales, & Dolphins)

Sunday, August 22nd, 2010

dolphin

What do humans, whales, and dolphins have in common?  Besides the obvious that they’re all mammals, warm blooded, and give birth to “live young”, here’s one similarity you might not have heard of.

Dolphins, whales, and humans are the only animals on the planet that require a one-to-one ratio of Omega-6 to Omega-3 essential fatty acids.

The term “essential” is used to imply that our body can’t make them (easily), and as such we need to get them from our diet.  How essential are they?  Studies on mice have shown deficiencies in these essential fats cause extreme health issues, while restoring those fats to their diets immediately reversed their health.

The Omega-6 fatty acids are used to increase inflammation, constrict blood vessels, and stimulate blood clotting – functions that are useful as part of the immune system.  Omega 3s do the opposite – thin the blood, decrease blood pressure, and in general help to increase immunity. Hence the need for the 1:1 balance of Omega 6s to Omega 3s.

So, how are we as humans doing to achieve that 1:1 ratio?

Unfortunately, not so good – at least here in the West.  Rather than an ideal 1:1 ratio of Omega 6s to Omega 3s, a typical American diet is more like a 20:1 ratio.  And many experts believe this imbalance is significantly correlated with the increases in asthma, heart disease, several cancers, and neurological disorders (including depression, aggression, ADHD, schizophrenia, Parkinson’s, MS, and Alzheimer’s).1 A UK prison study demonstrated a remarkable 37% drop in violent offences once Omega 3s were added to the prisoner’s diets.2 Countless studies have since demonstrated a correlation between decreased Omega 3 intake and increased depression rates.

But that major imbalance of Omega 6 to Omega 3 wasn’t always the case.

Our food sources have always been and remain rich in Omega 6s (seeds, nuts, vegetable oils, etc.).  And, our diets once were replete with Omega-3s as a result of the fish and meat we ate.  But with over farming and the dramatic increase in grain-fed animals and processed foods that is no longer the case.

The unfortunate truth is that many of us are now severely lacking in Omega 3s, an essential fatty acid that is crucial for optimal health.

In Part 3 of this series, I’ll discuss the various forms of Omega 3 and how to get what your body really needs.  To quote Dr. Abel, author of The DHA Story, “All men may be created equal, but not all [Omega 3] fatty acids are.”

[1] http://www.drweil.com/drw/u/QAA400149/balancing-omega-3-and-omega-6.html
[2] http://www.guardian.co.uk/politics/2006/oct/17/prisonsandprobation.ukcrime

The Importance of DHA – Part 1 (Eyesight)

Sunday, August 15th, 2010
One of our Healthy Humans doctors, Robert Abel, published a terrific book called The DHA Story – How Nature’s Super Nutrient Can Save Your Life (http://www.amazon.com/DHA-Story-Natures-Super-Nutrient/dp/1591200016/ref=sr_1_4?ie=UTF8&s=books&qid=1281887588&sr=8-4) that offers a ton of compelling evidence for getting enough DHA in our diets.
In this multi-part blog post, I’d like to highlight some of the incredibly powerful correlations between DHA and optimal health.
Having recently discovered the meaning of myopia (nearsightedness) and my slow-to-admit need for some “corrective action”, I began studying the eye and general “eye health”.  Turns out the retina (as well as the brain) is composed of up to 30% DHA!
As a matter of fact, DHA is a key component of all our cell membranes. DHA (docosahexaenoic acid) is an Omega-3 fatty acid molecule with 22 carbon chains and a carboxyl group at the end.  And a key element of this structure is that six of the 22 carbon chains, starting with the 3rd (hence the term Omega-3) have double bonds between them (the rest all have single bonds).  Conversely, Omega-6 fatty acids have their first double bond at the 6th carbon chain (and only contain between 2-4 double bonds).
More double bonds better help counter the effects of free radicals and improve cell to cell communication.  A study from the NIH (National Institutes of Health) showed that if DHA were replaced by its Omega-6 counterpart (DPA), significant vision deterioration resulted (along with many other health problems).  And there is a ton of additional research showing the correlation between DHA and good eyesight.
While fish oils are great sources of Omega 3s, most of these oils contain 80% EPA and only 20% DHA.  EPA, or Eicosapentaenoic acid, is a precursor to DHA and contains only 20-carbon chains, five of them with double bonds.  Unfortunately, our bodies are not very good at converting EPA to DHA, and as such need to get our DHA intake from what we eat.  So, along with a begrudgingly painful trip to the optometrist for corrective lenses, I’ll also be starting a DHA supplementation regimen in an effort to strengthen the “windows to my soul”.
In Part 2 of this series, I’ll talk about the differences between Omega-3s and Omega-6s and how humans, dolphins and whales are unique amongst the animal kingdom.

eyechartOne of our Healthy Humans doctors, Robert Abel, published a terrific book called The DHA Story – How Nature’s Super Nutrient Can Save Your Life that offers a ton of compelling evidence for getting enough DHA in our diets.

In this multi-part blog post, I’d like to highlight some of the incredibly powerful correlations between DHA and optimal health.

Having recently discovered the meaning of myopia (nearsightedness) and my slow-to-admit need for some “corrective action”, I began studying the eye and general “eye health”.  Turns out the retina (as well as the brain) is composed of up to 30% DHA!

As a matter of fact, DHA is a key component of all our cell membranes. DHA (docosahexaenoic acid) is an Omega-3 fatty acid molecule with 22 carbon chains and a carboxyl group at the end.  And a key element of this structure is that six of the 22 carbon chains, starting with the 3rd (hence the term Omega-3) have double bonds between them (the rest all have single bonds).  Conversely, Omega-6 fatty acids have their first double bond at the 6th carbon chain (and only contain between 2-4 double bonds).

More double bonds better help counter the effects of free radicals and improve cell to cell communication.  A study from the NIH (National Institutes of Health) showed that if DHA were replaced by its Omega-6 counterpart (DPA), significant vision deterioration resulted (along with many other health problems).  And there is a ton of additional research showing the correlation between DHA and good eyesight.

While fish oils are great sources of Omega 3s, most of these oils contain 80% EPA and only 20% DHA.  EPA, or Eicosapentaenoic acid, is a precursor to DHA and contains only 20-carbon chains, five of them with double bonds.  Unfortunately, our bodies are not very good at converting EPA to DHA, and as such need to get our DHA intake from what we eat.  So, along with a begrudgingly painful trip to the optometrist for corrective lenses, I’ll also be starting a DHA supplementation regimen in an effort to strengthen the “windows to my soul”.

In Part 2 of this series, I’ll talk about the differences between Omega-3s and Omega-6s and how humans, dolphins and whales are unique amongst the animal kingdom.

Health, Wellness, and Awareness

Thursday, August 13th, 2009

Know anyone with Diabetes? Almost one in ten are affected, including my dad.

In my new role as the CEO of a healthcare company, I spend a lot of time with medical doctors and in the midst of medical research. One of the things that surprised me quite a bit when I first began with Healthy Humans was how much compelling research around certain illnesses is all but unknown by the general public. And, I’m talking about evidence-based research that can really make a difference.

Even more surprising to me was how many chronic diseases could not only be kept in check, but in some cases completely reversed! While I’m not a medical doctor, I certainly have a vested interest in seeing people get better outcomes.

Today I read a powerful study[1] that is fairly dated – it was published in the Journal of Clinical Pathology in 1988 – however, the results of the research are just as relevant today. People with diabetes who take metformin (a popular diabetes medicine that helps with blood sugar control) have a significant risk of hypomagnesaemia – low magnesium levels in the blood. Not only are low magnesium levels a suggested risk factor for diabetic retinopathy (damage to the retina caused by complications from diabetes that can lead to blindness) but also arrhythmias (abnormal electrical activity in the heart).

The solution seems simple – if you are taking metformin, then be sure to consider taking a magnesium supplement. [Actually, metformin also seems to deplete the body of Vitamin B12, but I’ll save that for another discussion.]

You’d be shocked at how many people with diabetes don’t know this information.

[1] McBain AM, Brown IR, Menzies DG, Campbell IW. Effects of improved glycaemic control on calcium and mangnesium homeostasis in type II diabetes. J Clin Pathol 1988;41:933-35.

I’m Too Young For This

Saturday, July 18th, 2009

It isn’t hard to spot the modern day social media heroes when you look beyond the blitz of self-proclaimed “online media moguls” amassing their hordes of “friends” and “followers” anxiously awaiting the next i2y1bathroom-break posting.

Last week, a few of us from Healthy Humans met one of those “real” heroes who not only has a remarkable personal story, but is touching the lives of many through an exploding grass roots movement.

His name is Matthew Zachery, and the organization he founded is called I’m Too Young for This [I2Y]. At age 21, Matthew was diagnosed with brain cancer. Many told the young concert pianist he’d never play again, let alone have much of a future. Now at age 35 and having survived his condition, he has built an amazing organization focused on young adults with cancer.

The first thing I saw when I walked into his office within the NYU campus was a poster that read:

Got Cancer?
Under 40?
Sucks, huh?

Get busy living!

The challenge that Matthew shared with us is that most cancer survivorship rates have gone up over the past few decades as technology has evolved, education has improved, and treatments become more diverse. Except in the young adult (18-39) demographic, where survivorship rates have remained unchanged for nearly 30 years!

I2Y helps young adults with cancer to connect, share, and tap into resources for topics like healthcare, dating, financial support, insurance, fertility, depression, and many others. They’re now promoted in over 200 cancer centers and 9 countries. I2Y groups are spontaneously cropping up all over the world. Matthew hosts aBlogTalkRadio show each week from his office/studio. The name of the radio show is Stupid Cancer and listener/subscriber rates are exploding as people tune in to Matthew’s brilliant blend of wit, humility, sarcasm, irreverence, and charming personality.

Wonder what someone like Matthew would do when told he would never perform classical music again? Well, besides starting I2Y and an underground movement that would make any open source enthusiast proud, he recently released a CD of his own compositions calledScribblings (available on iTunes) – 10 tracks of blissful tranquility.

It’s an honor to meet people like Matthew Zachary who really are “changing the world”.

Pictured is Matthew proudly displaying his “rack” of circa-1984 Macintosh computers.